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Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model

Mathew et al. | Aug 11, 2019

Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model

Coronary Artery Disease (CAD) is the leading cause of death in the United States, and 81% of Acute Kidney Injury (AKI) patients in the renal fibrosis stage later develop CAD. In this study, Mathew and Joykutty aimed to create a cost-effective strategy to treat AKI and thus prevent CAD using a model of the zebrafish, Danio rerio. They first tested whether AKI is induced in Danio rerio upon exposure to environmental toxins, then evaluated nitrotyrosine as an early biomarker for toxin-induced AKI. Finally, they evaluated 4 treatments of renal fibrosis, the last stage of AKI, and found that the compound SB431542 was the most effective treatment (reduced fibrosis by 99.97%). Their approach to treating AKI patients, and potentially prevent CAD, is economically feasible for translation into the clinic in both developing and developed countries.

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Purification of Water by Aloe

Sharma et al. | Aug 19, 2016

Purification of Water by Aloe

The authors test the ability of aloe vera gel to purify water of four separate contaminants. Aloe reduced the levels of copper, iron, and phosphate, but not nitrate. Potential applications of this purification system are discussed.

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Different volumes of acetic acid affect the oxygen production of spinach leaves during photosynthesis

Wang et al. | Feb 24, 2023

Different volumes of acetic acid affect the oxygen production of spinach leaves during photosynthesis

The burning of fossil fuels, leading to an increased amount of carbon emissions, is the main cause of acid rain. Acid rain affects the process of photosynthesis, which makes the topic valuable to investigate. Our group utilizes plants to further investigate the relationship between pH value and photosynthesis. In this experiment, our group hypothesized that rain with a lower pH will decrease the rate of photosynthesis, causing less oxygen to be produced in the reaction.

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Rethinking the electric vehicle tax policy: prioritizing affordable solutions for environmental impact

Miao et al. | Jan 26, 2026

Rethinking the electric vehicle tax policy: prioritizing affordable solutions for environmental impact

Car emissions harm both the environment and human health, and current U.S. EV tax credits mainly benefit high-income households because EVs are expensive. This study evaluates U.S. vehicle emissions policies by analyzing 2022 national vehicle data to compare the fuel economy and greenhouse gas impacts of the current EV tax credit with a proposed policy that incentivizes hybrid vehicle purchases.

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