Browse Articles

A small town with low crime rates and relatively high education levels usually gives the perception of a safe and comfortable community. This study explored the connection between this perception, as defined by public opinion, and reality, as defined by US Census and FBI crime data.

Levy & Levy tackle the optimization of the coronary artery bypass graft, a life-saving surgical technique that treats artery blockage due to coronary heart disease. The authors develop a novel auto-suturing method that saves time, allows for an increased number of sutures, and improves graft quality over hand suturing. The authors also show that increasing the number of sutures from four to five with their new method significantly improves graft quality. These promising findings may help improve outcomes for patients undergoing surgery to treat coronary heart disease.

Coronary heart disease (CHD) is a global disease that causes fatal buildup of plaque in the arteries. Currently stents are placed in the artery for many patients with CHD to support proper blood flow. Here, the authors build a system to explore how the shape of the stent affects blood flow rate, a finding that can help optimize stents for patients.

Coronary artery bypass grafts are a common technique to treat coronary heart disease. The authors compared the efficacy of suturing and stapling techniques using an artificial heart pump and silicone tubing and found that suturing, while more time and skill intensive, held pressure in the tubing better than stapling.

Elevated acetylcholinesterase (AChE) activity contributes to cognitive decline and neurodegenerative diseases such as Alzheimer’s, motivating the search for more effective inhibitors with better bioavailability. This study used computational methods to design novel, non-toxic AChE inhibitors.

The authors looked at genes and pathways that are enriched in glioblastoma multiforme.

In this study the authors looked at the extract of Stephania tetrandra and its impact on symptoms related to obsessive compulsive disorder in fruit flies.

In this study, the authors design a series of new biaryl small molecules to target and block the binding pocket of the enzyme dihydropteroate synthase, which is important for prokaryotic biosynthesis of folic acid and could serve as better antimicrobial compounds.

In this study, the authors investigate an alternative way to kill bacteria other than the use of antibiotics, which is useful when considering antibiotic-resistance bacteria. They use bacteriophages, which are are viruses that can infect bacteria, and measure cell lysis. They make some important findings that these bacteriophage can lyse both antibiotic-resistant and non-resistant bacteria.

The most common atopic disease of the upper respiratory tract is allergic rhinitis. It is defined as a chronic inflammatory condition of nasal mucosa due to the effects of one or more allergens and is usually a long-term problem. The purpose of our study was to test the efficiency of apitherapy in allergic rhinitis healing by the application of honey bee pollen. Apitherapy is a branch of alternative medicine that uses honey bee products. Honey bee pollen can act as an allergen and cause new allergy attacks for those who suffer from allergic rhinitis. Conversely, we hoped to prove that smaller ingestion of honey bee pollen on a daily basis would desensitize participants to pollen and thus reduce the severity of allergic rhinitis.