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The authors looked at four members of the tetracycline antibiotic family/class against four different species of bacteria.

This study investigates the effects of the PROTAC compound A1874 on CT26 colon carcinoma cells, focusing on its ability to degrade the protein BRD4 and reduce cell viability. While A1874 had previously shown effectiveness in other colon cancer cell lines, its impact on CT26 cells was unknown.

In this study, the impact of fluorination of heterocyclic drug Allopurinol on its stability and other chemical properties is investigated.

Molecules which bind to proteins that aggregate abnormally in neurodegenerative diseases could be promising drugs for these diseases. In this study, Zhang, Wu, Zhang, and Dang simulate the binding behavior of various molecules to screen for candidates which could be promising candidates for drug development.

Identifying treatments that can stimulate hair growth use could help those struggling with undesirable hair loss. Here, the authors show that Fibroblast Growth Factors can stimulate the division of cells isolated from the mouse hair follicle. Their results suggest that this family of growth factors might be helpful in stimulating hair growth in living animals as well.

The authors test the effect of petroleum-based and bio-based microplastics on the growth of two microalgae species.

Childhood abuse has severe and lasting effects throughout an individual's life, and may even have long-term biological effects on individuals who suffer it. To learn more about the effects of abuse in childhood, Li and Yearwood analyze gene expression data to look for genes differentially expressed genes in individuals with a history of childhood abuse.

The authors investigate the ability of machine learning models to developing new drug-like molecules by learning desired chemical properties versus simply generating molecules that similar to those in the training set.

Studying cut-resistant socks for hockey players

The authors looked at the ability of berberine in combination with melatonin to have anticancer effects when tested in an in vitro cell model.