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In vitro Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers

Zhang et al. | Sep 02, 2020

<em>In vitro</em> Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers

Resveratrol is a type of stillbenoid, a phenolic compound produced in plants, that is known for its anti-inflammatory and anticancer effects. Many oligomers of resveratrol have recently been isolated their bioactivities remain unknown. Here, authors compared the bioactivities of resveratrol with natural dimers (ε-viniferin and gnetin H) and trimers (suffruticosol B and C). Results provide preliminary evidence that resveratrol oligomers could be potential preventive or therapeutic agents for cancers and other immune-related diseases

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Investigating the effects of glucose reintroduction on acutely starved HeLa cells

Puduru et al. | Jul 05, 2026

Investigating the effects of glucose reintroduction on acutely starved HeLa cells

Cancer cells rely heavily on glycolysis, but how they respond when glucose is reintroduced after acute starvation is not well understood. Using fluorescence lifetime imaging microscopy, students tracked metabolic changes in HeLa cells and found a rapid shift toward glycolysis within 20 minutes of glucose reintroduction, followed by heterogeneous recovery toward oxidative phosphorylation. These results highlight metabolic flexibility and variability in cancer cells, offering insights relevant to treatment resistance and therapeutic design.

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