The authors assess a genetic variant within a well-known interaction partner of huntingtin that has been linked to modifying the age of onset of Huntington's disease.
Read More...Impact of TCERG1 SNP on gene expression and protein interactome in Huntington’s disease
The authors assess a genetic variant within a well-known interaction partner of huntingtin that has been linked to modifying the age of onset of Huntington's disease.
Read More...Examining the impact of the sympathetic nervous system on short-term memory
The authors looked at how activation of the sympathetic nervous system impacts short-term memory.
Read More...Applying machine learning to breast cancer diagnosis: A high school student’s exploration using R
The authors combine fine needle aspiration biopsy and machine learning algorithms to develop a breast cancer detection method suitable for resource-constrained regions that lack access to mammograms.
Read More...Using advanced machine learning and voice analysis features for Parkinson’s disease progression prediction
The authors looked at the ability to use audio clips to analyze the progression of Parkinson's disease.
Read More...Strain selective in vitro and in silico structure activity relationship of tetracycline antibiotics
The authors looked at four members of the tetracycline antibiotic family/class against four different species of bacteria.
Read More...Citrate and lactate drive glioblastoma progression via activation of tumor-associated macrophages
The authors looked at the impact of citrate and lactate on glioblastoma progression. Their results provide important insights for future immunotherapies aimed at treating glioblastoma.
Read More...An assessment of controllable etiological factors involved in neonatal seizure using a Monte Carlo model
The authors used Monte Carlo simulations to assess the impacts of various factors on neonatal seizure risk.
Read More...Associations between fentanyl usage and social media use among U.S. teens
Here the authors aimed to understand factors influencing adolescent fentanyl exposure, hypothesizing a positive association between social media usage, socioeconomic factors, and fentanyl abuse among U.S. teens. Their analysis of the Monitoring the Future dataset revealed that a history of suspension and use of marijuana or alcohol were linked to higher fentanyl use, and while not statistically significant, a notable positive correlation between social media use and fentanyl frequency was observed.
Read More...Mechanism and cytotoxicity of A1874 proteolysis targeting chimera on CT26 colon carcinoma cell line
This study investigates the effects of the PROTAC compound A1874 on CT26 colon carcinoma cells, focusing on its ability to degrade the protein BRD4 and reduce cell viability. While A1874 had previously shown effectiveness in other colon cancer cell lines, its impact on CT26 cells was unknown.
Read More...The effect of default opt-ins and social proof tags on high-stake decision-making in an e-commerce context
Default opt-ins and social proof tags effect on decision making in an e-commerce context
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