Browse Articles

Using the COmplex PAthway SImulator, Stage Analysis, and Chemical Kinetics to Develop a Novel Solution to Lower Tau Concentrations in Alzheimer’s Disease

Carroll et al. | Sep 28, 2020

Using the COmplex PAthway SImulator, Stage Analysis, and Chemical Kinetics to Develop a Novel Solution to Lower Tau Concentrations in Alzheimer’s Disease

In this study, the authors ask whether a Tau immunotherapy treatment, Hsp70 protein treatment, or dual treatment approach of both the Tau imunotherapy treatment and Hsp70 protein treatment leads to a greater reduction in Tau protein concentration in Alzheimer's disease. Overall, they conclude that the effectiveness of the treatment ultimately relies on the stage of Alzheimer’s.

Read More...

Electrocatalytic oxidation of furfural on Co3O4/nickel foam catalyst: performance and mechanistic study

Song et al. | Jul 19, 2026

Electrocatalytic oxidation of furfural on Co<sub>3</sub>O<sub>4</sub>/nickel foam catalyst: performance and mechanistic study
Image credit: Shraga kopstein

In this study, the authors hypothesized that the unique redox properties of cobalt oxide (Co3O4), combined with the conductive nature of the nickel foam (NF) substrate, synergistically enhances the catalytic performance for furfural oxidation. The study showed successful synthesis of Co3O4 nanoflowers directly grown on NF and tested their capacity to serve as a highly efficient electrocatalyst for furfural oxidation. Beyond furfural oxidation, this study also offers broader implications for sustainable chemistry by establishing design principles for efficient nucleophilic oxidation reaction catalysts, demonstrating an energy-saving alternative to conventional oxygen evolution reaction-coupled processes, and showcasing how biomass conversion can be integrated with renewable energy systems.

Read More...

Enhanced brain arteries and aneurysms analysis using a CAE-CFD approach

Saravanan et al. | Mar 02, 2025

Enhanced brain arteries and aneurysms analysis using a CAE-CFD approach
Image credit: Vineet Saravanan

Here, recognizing that brain aneurysms pose a severe threat, often misdiagnosed and leading to high mortality, particularly in younger individuals, the authors explored a novel computer-aided engineering approach. They used magnetic resonance angiography images and computational fluid dynamics, to improve aneurysm detection and risk assessment, aiming for more personalized treatment.

Read More...

Model selection and optimization for poverty prediction on household data from Cambodia

Wong et al. | Sep 29, 2023

Model selection and optimization for poverty prediction on household data from Cambodia
Image credit: Paul Szewczyk

Here the authors sought to use three machine learning models to predict poverty levels in Cambodia based on available household data. They found teat multilayer perceptron outperformed the other models, with an accuracy of 87 %. They suggest that data-driven approaches such as these could be used more effectively target and alleviate poverty.

Read More...