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Quantifying right atrial dilation relative to atrial septal defect size using an experimental model

Lee et al. | Dec 06, 2025

Quantifying right atrial dilation relative to atrial septal defect size using an experimental model
Image credit: jesse orrico

To address the limitations in predicting the severity of Atrial Septal Defect (ASD), here the authors utilized a fluid-filled chamber model to quantify the relationship between defect size and right atrial fluid output. The findings confirmed that larger ASD diameters result in a linear increase in fluid output, validating a cost-effective model that can improve clinical prognosis and treatment planning for heart failure risks.

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Cell cytotoxicity and pro-apoptosis on MCF-7 cells using polyherbal formulation, MAT20

Tarigopula et al. | Feb 17, 2023

Cell cytotoxicity and pro-apoptosis on MCF-7  cells using polyherbal formulation, MAT20

The purpose of this study was to test the anti-cancer properties and pro-apoptotic effects of the polyherbal formulation MAT20 as a complementary treatment. Moringa oleifera (Moringa), Phyllanthus emblica (Amla) and Ocimum sanctum (Tulsi), these 3 herbs were used to formulate MAT20, which contain phytochemicals that are known to display anti-cancer properties. In this study, we hypothesized that MCF-7 breast cancer cells treated with MAT20 would show increased cytotoxicity compared to its individual plant extracts.

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The Bioactive Ingredients in Niuli Lactucis Agrestibus Possess Anticancer Effects

Zhu et al. | Sep 17, 2019

The Bioactive Ingredients in Niuli Lactucis Agrestibus Possess Anticancer Effects

In​ the​ field​ of​ medicine,​ natural​ treatments​ are​ becoming ​increasingly ​vital ​towards ​the ​cure ​of ​cancer. Zhu et al. wanted to investigate the effects of lettuce extract on cancer cell survival and proliferation. They used an adenocarcinoma cell line, COLO320DM, to determine whether crude extract from a lettuce species called Niuli​ Lactucis Agrestibus​ would affect cancer cell survival, migration, and proliferation. They found that Niuli extract inhibited cancer cell survival, increased expression of cell cycle inhibitors p21 and p27, and inhibited migration. However, Niuli extract did not have these effects on healthy cells. This work reveals important findings about a potential new source of anti-colorectal cancer compounds.

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Antibiotic Residues Detected in Commercial Cow’s Milk

Memili et al. | Mar 18, 2015

Antibiotic Residues Detected in Commercial Cow’s Milk

Antibiotics are oftentimes used to treat mastitis (infection of the mammary gland) in dairy cows. Regulations require that milk from these cows be discarded until the infection has cleared and antibiotic residues are no longer detectable in the cow's milk. These regulations are in place to protect consumers and to help prevent the rise of antibiotic resistant bacteria. In this study, the authors test milk samples from 10 milk suppliers in the Greensboro, NC to see if they contain detectable levels of antibiotic residues.

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Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

Saha et al. | Nov 18, 2023

Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

In this article the authors created an interaction map of proteins involved in colorectal cancer to look for driver vs. non-driver genes. That is they wanted to see if they could determine what genes are more likely to drive the development and progression in colorectal cancer and which are present in altered states but not necessarily driving disease progression.

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