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Nitric Oxide Synthesis/Pathway Inhibitors in Daphnia magna Reverse Alcohol-Induced Heart Rate Decrease

Gunturi et al. | Sep 17, 2019

Nitric Oxide Synthesis/Pathway Inhibitors in Daphnia magna Reverse Alcohol-Induced Heart Rate Decrease

Chronic alcohol consumption can cause cardiac myopathy, which afflicts about 500,000 Americans annually. Gunturi et al. wanted to understand the effects of alcohol on heart rate and confirm the role of nitric oxide (NO) signaling in heart rate regulation. Using the model organism Daphnia magna, a water crustacean with a large, transparent heart, they found that the heart rate of Daphnia magna was reduced after treatment with alcohol. This depression could be reversed after treatment with inhibitors of NO synthesis and signaling. Their work has important implications for how we understand alcohol-induced effects on heart rate and potential treatments to reverse heart rate depression as a result of alcohol consumption.

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Examining the impact of consecutive losses on gambling: When do we decide to quit?

Kim et al. | Apr 28, 2026

Examining the impact of consecutive losses on gambling: When do we decide to quit?
Image credit: Kim, Cragun, and Kim

This article explored the question of when do people decide to stop gambling and further tries to extrapolate why people stop gambling at that point. Their study showed that people tend to quit gambling after 4 consecutive losses, significantly more than 1-3 consecutive losses or a win previous to quitting. They also found that participants commonly quit at a point value approximately 5 points greater than or less than their starting balance. The authors concluded that these results may be important in understanding how to cut down on excessive gambling or in creating policies that make it easier for people to disengage from gambling.

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How CAFOs affect Escherichia coli contents in surrounding water sources

Lieberman et al. | Feb 24, 2023

How CAFOs affect <i>Escherichia coli</i> contents in surrounding water sources
Image credit: CDC

Commercial Concentrated Animal Feeding Operations (CAFOs) produce large quantities of waste material from the animals being housed in them. These feedlots found across the United States contain livestock that produce waste that results in hazardous runoff. This study examines how CAFOs affect water sources by testing for Escherichia Coli (E. coli) content in bodies of water near CAFOs.

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How planarians are affected by mouthwash and cough syrup

Mebane et al. | Nov 14, 2021

How planarians are affected by mouthwash and cough syrup

Since cough syrup and mouthwash are commonly used items and often end up flushed down the drain or toilet, they can eventually find their way into into freshwater waterways which can be harmful to many marine organisms, such as planarians (aquatic flatworms). To investigate the effects of these substances on planarians, the authors considered different concentrations of Listerine mouthwash and Robitussin syrup along with their active ingredients. By using a behavioral assay, they identified that the active ingredients of cough syrup detrimentally affect planarian behavior. They suggest that these findings could be used to guide disposal methods to lessen detrimental effects on aquatic life.

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