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Here the authors investigated a combination therapy to target the Kirsten rat sarcoma viral oncogene homolog mutation in lung cancer, by analyzing publicly available data. Their findings indicate that the combination therapy of CA170 and Kvax enhances helper T cell function and improves cytotoxic T lymphocyte infiltration, while Kvax alone drives plasma and memory B cell proliferation.

The authors employ computational protein design to identify a mini-protein with the potential to enhance binding of the tight junction protein, claudin-5, at the blood-blood barrier with therapeutic potential for neurodegenerative diseases.

The authors looked the ability of sound sensors to predict clogged pipes when the sound intensity data is run through a machine learning algorithm.

The authors test whether coating stainless steel orthopedic screws in silver will promote calcium precipitation to improve orthopedic implant integration into bone.

The authors looked at ways to provide better forecasting on website traffic. They found that deep learning models performed better than statistical models.

The authors develop a machine learning method to reduce misclassification of objects in safety-critical applications such as medical diagnosis.

The authors looked factors that could lead to earlier diagnosis of cardiovascular disease thereby improving patient outcomes. They found that advances in imaging and electrocardiography contribute to earlier detection of cardiovascular disease.

Arrhythmias vary in type and treatment, and ECGs are used to detect them, though human interpretation can be inconsistent. The researchers tested four tree-based algorithms (gradient boosting, random forest, decision tree, and extra trees) on ECG data from over 10,000 patients.

The authors use machine learning on MRI images of brain tissue to predict tumor onset as an avenue for early detection of brain cancer.

Here the authors explored the development of biodegradable bioplastic films derived from mango peels as a sustainable solution to plastic pollution and greenhouse gas emissions from fruit waste. They optimized the film's mechanical properties and water resistance through adjusting processing conditions and incorporating plasticizers and a hydrophobic coating, ultimately demonstrating its potential as a bacteriostatic and biodegradable alternative to conventional plastic food wrap.