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RNAi-based Gene Therapy Targeting ZGPAT Promotes EGF-dependent Wound Healing

Lee et al. | Nov 15, 2021

RNAi-based Gene Therapy Targeting ZGPAT Promotes EGF-dependent Wound Healing

Wound-healing involves a sequence of events, such as inflammation, proliferation, and migration of different cell types like fibroblasts. Zinc Finger CCCH-type with G-Patch Domain Containing Protein (ZGPAT), encodes a protein that has its main role as a transcription repressor by binding to a specific DNA sequence. The aim of the study was to find out whether inhibiting ZGPAT will expedite the wound healing process by accelerating cell migration. This treatment strategy can provide a key to the development of wound healing strategies in medicine and cellular biology.

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Effects of common supplements on human platelet aggregation in vitro

Prabhakar et al. | Apr 16, 2025

Effects of common supplements on human platelet aggregation in vitro
Image credit: The authors

There is a need for safe and effective therapies to prevent platelet aggregation associated with cardiovascular diseases. Prabhakar and Prabhakar test to see whether dietary supplements claiming to reduce cardiovascular disease risk will affect aggregation of human platelets.

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A novel approach for predicting Alzheimer’s disease using machine learning on DNA methylation in blood

Adami et al. | Sep 20, 2023

A novel approach for predicting Alzheimer’s disease using machine learning on DNA methylation in blood
Image credit: National Cancer Institute

Here, recognizing the difficulty associated with tracking the progression of dementia, the authors used machine learning models to predict between the presence of cognitive normalcy, mild cognitive impairment, and Alzheimer's Disease, based on blood DNA methylation levels, sex, and age. With four machine learning models and two dataset dimensionality reduction methods they achieved an accuracy of 53.33%.

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Effectiveness of Biodegradable Plastic in Preventing Food Spoilage

Zhang et al. | Mar 20, 2012

Effectiveness of Biodegradable Plastic in Preventing Food Spoilage

Most people put little thought into the type of plastic wrap they use to store their leftovers. This study investigates the differences between biodegradable plastic wrap and non-biodegradable plastic wrap in their ability to prevent food spoilage. Does one work better than the other? Read more to find out!

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