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The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.

Dhar and colleagues established a Type II diabetes mellitus (T2DM) model in fruit flies, using this model to induce insulin resistance and characterize the effects Resveratrol and Pterostilbene on a number of growth and activity metrics. Resveratrol and Pterostilbene treatment notably overturned the weight gain and glucose levels. The results of this study suggest that Drosophila can be utilized as a model organism to study T2DM and novel pharmacological treatments.

Chemicals used in fertilizers and pesticides often end up in nearby bodies of water due to runoff and may have negative impacts on these important ecosystems. In this study, the authors use water containing different nitrogen levels to investigate the effect on the growth of the English daisy.

Environment affects the progression of life, especially at the cellular level. This study investigates multiple 3-dimensional growth environments, also known as scaffolds or hydrogels, and their effect on the growth of a type of cells called fibroblasts. These results suggest that a scaffold made of collagen and polyethylene glycol are favorable for cell growth. This research is useful for developing implantable devices to aid wound healing.

In this study, the authors investigate whether antibiotic-resistant bacteria can be found in everyday locations. To do this, they collected samples from multiple high-trafficked areas in Cambridge, MA and grew them in the presence and absence of antibiotics. Interestingly, they grew bacterial colonies from many locations' samples, but not all could grow in the presence of ampicillin. These findings are intriguing and relevant given the rising concern about antibiotic-resistant bacteria.

Consumers in India and the United Arab Emirates live in very different economic and cultural environments, and this study set out to measure how that shapes the way they shop and pay. Surveying 50 people in each country, they found that Indian consumers were more price-sensitive and favored cash, while UAE consumers prioritized convenience, gravitating toward credit cards, mobile wallets, and online shopping. The results offer practical insight for retailers, marketers, and policymakers working across these two fast-growing but culturally distinct markets.

In this study, the authors examine the relationship between ESG (Environmental, Social, and Governance) factors on financial performance of Vietnamese media companies, as measured by ROA and ROE. They find that ESG is positively correlated with financial performance, as is sales growth. They also find that financial leverage is negatively correlated with ROA. Overall, this is a quality study, although the methods section requires more detail.

In this study, the authors hypothesized that the unique redox properties of cobalt oxide (Co₃O₄), combined with the conductive nature of the nickel foam (NF) substrate, synergistically enhances the catalytic performance for furfural oxidation. The study showed successful synthesis of Co₃O₄ nanoflowers directly grown on NF and tested their capacity to serve as a highly efficient electrocatalyst for furfural oxidation. Beyond furfural oxidation, this study also offers broader implications for sustainable chemistry by establishing design principles for efficient nucleophilic oxidation reaction catalysts, demonstrating an energy-saving alternative to conventional oxygen evolution reaction-coupled processes, and showcasing how biomass conversion can be integrated with renewable energy systems.

Microplastic pollution is a pressing environmental issue, particularly in the context of its potential impacts on ecosystems and human health. In this study, we explored the ability of plants, specifically those cultivated for human consumption, to absorb microplastics from their growing medium. We found no evidence of microplastic absorption in both intact and mechanically damaged roots. This outcome suggests that microplastics larger than 10 μm may not be readily absorbed by the root systems of leafy crops such as lettuce (L. sativa).

Agricultural fertilizer application is a key innovation in providing enough food to feed the world. Fertilizers come in various types and farmers must choose which fertilizer is the best for their applications. To learn more about the effectiveness of various fertilizers, Wilson and Rasmus studied the effects of natural and chemical fertilizers on growth of basil plants.