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Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

Saha et al. | Nov 18, 2023

Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

In this article the authors created an interaction map of proteins involved in colorectal cancer to look for driver vs. non-driver genes. That is they wanted to see if they could determine what genes are more likely to drive the development and progression in colorectal cancer and which are present in altered states but not necessarily driving disease progression.

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Simulating single versus cocktail antibiotic effects on the human gut microbiome

Patel et al. | Jul 19, 2026

Simulating single versus cocktail antibiotic effects on the human gut microbiome
Image credit: Volodymyr Hryshchenko

This study, uses SimulATe to model changes in microbial diversity and community structure upon administering a cocktail of antibiotics versus a single antibiotic. The authors hypothesized that antibiotic cocktails, particularly those combining broad-spectrum drugs like tetracyclines and trimethoprims, would cause a more significant reduction in gut microbial diversity compared to single-drug treatments. The findings confirmed a greater loss of microbial diversity with combinatorial treatments compared to single-drug treatments. While individual antibiotics dynamically reshaped the surviving species of the microbiome, antibiotic cocktails frequently cleared all species of the gut microbiome.

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A cross-cultural analysis of consumer behavior and payment preferences: Insights from India and the United Arab Emirates

Bansal et al. | Sep 01, 2026

A cross-cultural analysis of consumer behavior and payment preferences: Insights from India and the United Arab Emirates

Consumers in India and the United Arab Emirates live in very different economic and cultural environments, and this study set out to measure how that shapes the way they shop and pay. Surveying 50 people in each country, they found that Indian consumers were more price-sensitive and favored cash, while UAE consumers prioritized convenience, gravitating toward credit cards, mobile wallets, and online shopping. The results offer practical insight for retailers, marketers, and policymakers working across these two fast-growing but culturally distinct markets.

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An analysis of the mechanical properties of fencing swords, and implications for weapon selection

Redmond et al. | Aug 24, 2026

An analysis of the mechanical properties of fencing swords, and implications for weapon selection
Image credit: Jonathan Falcon

The sword is the most important piece of equipment a fencer uses. In this study, we compared the mechanical and physical properties of two of the most common types of swords used in foil fencing.We that found that maraging steel blades had a significantly greater stiffness and were damped more effectively than low carbon steel blades. These properties affect how the blade behaves during particular maneuvers and techniques, and our findings therefore provide useful insights for fencers who want to select the optimal sword configuration to suit their personal style.

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Leveraging transfer learning with convolutional neural networks for cardiovascular disease detection

Chen et al. | May 25, 2026

Leveraging transfer learning with convolutional neural networks for cardiovascular disease detection
Image credit: Stephen Andrews

This study shows the efficacy of leveraging transfer learning, specifically from residual networks, to detect CVDs and possible signs of CVDs. The findings indicate that leveraging transfer learning from residual networks alongside medical professionals is a highly promising approach for CVD detection and diagnosis, warranting further investigation.

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Eye color, visual acuity and photophobia: How eye color affects light sensitivity

Spencer et al. | May 20, 2026

Eye color, visual acuity and photophobia: How eye color affects light sensitivity

This study examined whether eye color affects photophobia and vision in elementary school students and staff, finding no significant relationship between eye color, light sensitivity, or visual acuity. However, photophobia was common across age groups, highlighting the need for greater awareness of light sensitivity in learning environments.

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